OH Frazier, MD

OH Frazier, MD, es una leyenda viva y célebre por sus contribuciones al campo del soporte circulatorio mecánico y tratamientos pioneros para pacientes que padecen insuficiencia cardíaca. Realizó más de 1,200 trasplantes de corazón e implantó más de 900 dispositivos de asistencia ventricular izquierda, más que cualquier otro cirujano del mundo. En la actualidad se desempeña como codirector del Centro de Investigación Intervencionista y Quirúrgica Preclínica del THI.

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Durante más de 30 años, el Dr. OH Frazier ha sido un pionero en el tratamiento de la insuficiencia cardíaca grave y en los campos de trasplante de corazón y dispositivos artificiales que puede utilizarse para sustituir o ayudar a la acción de bombeo del corazón humano. Como resultado de su trabajo, se convirtió en uno de los mejores cirujanos de trasplante y soporte circulatorio mecánico del mundo. El Dr. Frazier realizó más de 1,200 trasplantes de corazón e implantó más de 900 dispositivos de asistencia ventricular izquierda, más que cualquier otro cirujano en el mundo.

El interés del Dr. Frazier en el soporte circulatorio mecánico comenzó en 1969, cuando, como estudiante en el Baylor College of Medicine, escribió un artículo de investigación sobre el corazón artificial total experimental, que fue implantado por primera vez en 1969 por el Dr. Denton Cooley. Durante las décadas de 1970 y 1980, el Dr. Frazier continuó el trabajo experimental para desarrollar un dispositivo implantable de asistencia ventricular izquierda (LVAD, por sus siglas en inglés) para ayudar al corazón que falla. En 2011, el Dr. Frazier implantó con éxito el primer corazón artificial total de flujo continuo usando dos HeartMate II LVAD para reemplazar el corazón defectuoso de un paciente.

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Posiciones del Instituto del Corazón de Texas

Proyectos actuales

Intereses

Educación

  • De licenciatura:

    Universidad de Texas

  • Escuela de Medicina:

    Baylor College of Medicine

  • Residencia:

    Baylor College of Medicine

  • Becas:

    Instituto del Corazón de Texas/Facultad de Medicina de Baylor

Afiliaciones académicas y clínicas

  • Baylor College of Medicine
  • Centro Médico Baylor St. Luke

Especificaciones

  • Junta Americana de Cirugía Torácica
  • Junta Americana de Cirugía

Honores, premios y membresías

Publicaciones

4862227 SE7HDD49 1 alternativas-a-la-experimentación-con-animales 10 datos desc Frazier 1910 https://www.texasheart.org/wp-content/plugins/zotpress/
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Nissim, L., Karnik, S., Smith, PA et al. (2023). El aprendizaje automático basado en dinámica de fluidos computacional permite la optimización del diseño geométrico de las palas NeoVAD. Sci Rep 13, 7183. https://doi.org/10.1038/s41598-023-33708-9.
Devich, R., Neuendorff, NR, Frazier, OH et al. (2023). Estimulación hematopoyética durante el soporte Impella 5.5 para evitar transfusiones en un Testigo de Jehová. ASAIO J.. https://doi.org/10.1097/MAT.0000000000001944.
Chu, MWA, Ruel, M., Graeve, A. et al. (2023). Warfarina en dosis baja versus estándar después del reemplazo mecánico de la válvula mitral: un ensayo aleatorizado. Ann Thorac Cirugía 115, 929-938. https://doi.org/10.1016/j.athoracsur.2022.12.031.
Smith, PA, Wang, Y. y Frazier, OH (2023). La evolución de las bombas de sangre rotativas de flujo axial implantables y duraderas. Tex Corazón Inst J 50, E227908. https://doi.org/10.14503/THIJ-22-7908.
Kiang, S., Nissim, L., Tedesco, V. et al. (2022). Modelado de un rodamiento de levitación magnética con optimización de hemocompatibilidad CFD. En 2022 IEEE 20.a Conferencia bienal sobre computación de campo electromagnético (CEFC) (1–2). Denver, CO, EE. UU.: IEEE. https://doi.org/10.1109/CEFC55061.2022.9940768.
Moctezuma-Ramírez, A., Elgalad, A., Handy, K. et al. (2022). Hemodinámica basal, incluido el flujo sanguíneo aórtico y pulmonar en un modelo bovino crónico. Cirugías 3, 192-202. https://doi.org/10.3390/surgeries3030021.
Selzman, CH, Feller, ED, Walker, JC et al. (2022). El dispositivo de asistencia ventricular izquierda Jarvik 2000: resultados del ensayo Bridge to Transplant de Estados Unidos. ASAIO J.. https://doi.org/10.1097/MAT.0000000000001750.
Broda, CR, Frankel, WC, Nair, AP y col. (2022). Soporte con dispositivo de asistencia ventricular de flujo continuo en cardiopatías congénitas en adultos: una experiencia multicéntrica de 15 años de soporte temporal y duradero. ASAIO J.. Disponible en: https://doi.org/10.1097/MAT.0000000000001853.
Lamba, HK, Musfee, FI, Chatterjee, S. et al. (2021). La influencia de la diálisis preoperatoria en la supervivencia después de la implantación de un dispositivo de asistencia ventricular izquierda de flujo continuo. Interactuar Cardiovasc Thorac Surg, ivab357. https://doi.org/10.1093/icvts/ivab357.
Balachandran, I., Frazier, OH y Rogers, JG (2021). Hacer lo incorrecto por las razones correctas: la desaparición del HVAD. J Thorac Cirugía Cardiovasc, S0022-5223(21)01656–1. https://doi.org/10.1016/j.jtcvs.2021.10.058.

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El Dr. OH Frazier recibió un doctorado honorario de la Universidad Estatal de Tarleton

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Dr. OH Frazier honrado con el premio Lifetime Achievement Award de ASAIO

El Dr. OH “Bud” Frazier ha recibido el prestigioso premio Pushpa y Kewal Krishan Gupta Lifetime Achievement Award in Development...

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El Dr. OH Frazier recibirá el premio inaugural Pushpa y Kewal Krishan Gupta Lifetime Achievement Award en el desarrollo de terapias para enfermedades cardiovasculares y pulmonares de la ASAIO

La Junta Directiva de ASAIO ha nombrado al Dr. OH Frazier, ganador del prestigioso premio Pushpa y Kewal Krishan Gupta Lifetime...

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